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Dr Amy Shacaluga

MBBCh MRCOG DFSRH Dip Lifestyle Medicine

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The Perimenopause:

  • Writer: amyshacaluga
    amyshacaluga
  • Mar 17
  • 3 min read

The Pitfalls of Perimenopause: 


Perimenopause is the hormonal transition that precedes menopause and is typically  characterised by increasing changes in ovarian hormone production (particularly oestradiol and progesterone). For many of us, this brings with it a widening mismatch between “how you look on paper” and how you feel day-to-day. The clinical challenge is that symptoms can be intermittent, overlap with other conditions, and be misattributed to stress, ageing, or primary mood disorder—leading to delayed recognition and fragmented care.

A lifestyle medicine and functional medicine lens is helpful here: it validates perimenopause as a real physiological transition, while also assessing the broader drivers that amplify symptoms (sleep disruption, blood sugar volatility, stress physiology, inflammation load, nutrient status, and thyroid/metabolic health). The goal is not to “biohack hormones,” but to reduce symptom burden, protect cardiometabolic health, and create a personalised plan aligned with your values and risk profile.


Pitfall 1: Let’s dress our symptoms us as  “just stress” or “just ageing”

One of the most common pitfalls is minimisation—by clinicians, workplaces, and often by women themselves. Perimenopause can affect sleep, mood, cognition (“brain fog”), body composition, cardiometabolic risk markers, libido, and menstrual patterns. When symptoms are framed as purely psychological or purely “hormonal,” opportunities are missed to address actual drivers.

Reframe: perimenopause is a neuroendocrine transition—brain, hormones, metabolism and lifestyle are tightly linked. I emphasise the breadth of symptoms and the importance of foundational levers such as nutrition, resistance training, sleep, and selected supplements.¹


Pitfall 2: Under-treating sleep disruption

Sleep disturbance is often an early and high-impact feature of perimenopause. Poor sleep worsens hot flush threshold, increases appetite signalling, impairs glucose regulations well as reducing stress tolerance.

Let's reframe by acknowledging the importance of combining behavioural foundations (sleep timing, caffeine/alcohol boundaries, light exposure, calming routines) with thoughtful, individualised support where appropriate.²


“ If sleep is not addressed, many other interventions underperform”.


Pitfall 3: Responding to body composition changes with “eat less, do more cardio”

During perimenopause, many women experience changes in body composition and fat distribution (often central/visceral). A frequent pitfall is aggressive calorie restriction paired with escalating cardio, which can worsen fatigue, appetite, and stress physiology—while undermining muscle mass (a major protective factor for metabolic health and healthy ageing).

Prioritise: Progressive resistance training as well as  listening to your body. Tailor this to your cycles.


Pitfall 4: The blood sugar rollercoaster

Perimenopause can coincide with increasing glucose variability (often driven by disrupted sleep, stress load, changing body composition, and lower activity). This can present as energy crashes, irritability and cravings (especially late at night) with some over night wakes.

A functional medicine approach doesn’t assume everyone needs extensive testing. Instead, it uses a structured, symptom-led strategy. Hero protein forward breakfasts, post meal movement and sleep restoration.


Pitfall 5: Treating stress as an “optional add-on”

Stress physiology is not a soft variable; it is a biological amplifier. When stress is chronic and recovery is inadequate,  unwanted symptoms worsen (in spite of your other bolstered foundations).

The functional medicine model explicitly includes stress and resilience capacity as part of the clinical picture, not an afterthought. IFM frames the transition as an opportunity for personalised, whole-person strategies that reduce symptom burden and protect long-term health.³


Pitfall 6: Attributing everything to perimenopause (and missing other diagnoses)

The opposite pitfall is assuming perimenopause explains everything. Several conditions commonly overlap with midlife symptoms and should be considered when symptoms are persistent, severe, or atypical:

• thyroid dysfunction

• suboptimal haematinics

• sleep apnoea

• medication effects (including SSRIs/SNRIs, stimulants, antihistamines, etc.)

• alcohol-related sleep fragmentation


FAQs:

Do supplements help?


Sometimes—selectively and symptom-led. Supplements are not a substitute for sleep, training, and nutrition foundations. If used, they should be chosen based on symptom profile, medical history, and interactions with medications.


Will I need hormones?


Not always. Some women do very well with lifestyle interventions alone; others benefit from hormonal or non-hormonal therapies, depending on symptom burden, risk factors, and personal preferences. A risk–benefit discussion with an appropriately trained clinician is key.

 
 
 

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